Next available departures

Next departures for Brno to Prague on July 30
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	CheapestFastest
Vlak společnosti Gepard Express	4:00pm	bus station Grand	2h 25m	6:25pm	Vaclav Havel Airport Prague	No tags
	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	No tags
	12:10pm	Hotelu Grand	3h 15m	3:25pm	PRG Airport	No tags
	6:30am	Hotelu Grand	2h 30m	9:00am	Florenc	No tags
	1:10pm	Hotelu Grand	3h 30m	4:40pm	PRG Airport	No tags
	7:00am	Hotelu Grand	2h 55m	9:55am	Florenc	No tags
	8:50pm	Hotelu Grand	3h 15m	12:05am	PRG Airport	No tags

Next departures for Brno to Prague on July 31
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	CheapestFastest
	2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
Vlak společnosti Gepard Express	12:00pm	bus station Grand	2h 25m	2:25pm	Vaclav Havel Airport Prague	No tags
	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags
	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express	4:00pm	bus station Grand	2h 25m	6:25pm	Vaclav Havel Airport Prague	No tags
	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	No tags
	12:10pm	Hotelu Grand	3h 15m	3:25pm	PRG Airport	No tags

Next departures for Brno to Prague on August 1
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	Cheapest
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
	2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
Vlak společnosti Gepard Express	12:00pm	bus station Grand	2h 25m	2:25pm	Vaclav Havel Airport Prague	No tags
RegioJet + RegioJet	2:00am	Hotelu Grand	3h 46m	5:46am	Hlavní nádraží	No tags
	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express	4:00pm	bus station Grand	2h 25m	6:25pm	Vaclav Havel Airport Prague	No tags
	7:00am	Hotelu Grand	2h 55m	9:55am	Florenc	No tags

Next departures for Brno to Prague on August 2
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	Cheapest
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express	1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
	2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express	12:00pm	bus station Grand	2h 25m	2:25pm	Vaclav Havel Airport Prague	No tags
	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	No tags

Next departures for Brno to Prague on August 3
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:00pm	Hotelu Grand	2h 30m	8:30pm	Florenc	Cheapest
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express	1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
	2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express	10:00am	bus station Grand	2h 25m	12:25pm	Vaclav Havel Airport Prague	No tags
	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on August 4
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:00pm	Hotelu Grand	2h 30m	8:30pm	Florenc	Cheapest
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express	1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
	2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express	6:00am	bus station Grand	2h 25m	8:25am	Vaclav Havel Airport Prague	No tags
	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on August 5
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:00pm	Hotelu Grand	2h 30m	8:30pm	Florenc	Cheapest
	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
	2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
Vlak společnosti Gepard Express	6:00am	bus station Grand	2h 25m	8:25am	Vaclav Havel Airport Prague	No tags
	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags
	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express	8:00am	bus station Grand	2h 25m	10:25am	Vaclav Havel Airport Prague	No tags
	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	No tags

Last refresh of the prices: Yesterday at 10:42 PM CEST.

Compare 2 ways to go from Brno to Prague

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 2 hours 35 minutes and with fares starting at just HK$81, it presents an excellent value for a comfortable ride.

65bus per day

2h 35mAverage Duration

117 milesDistance

5kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceHK$81 - HK$315	Average Duration2h 35m	CO₂ emissions 5kg CO₂e
Train	Average PriceHK$100 - HK$579	Average Duration2h 55m	CO₂ emissions 4kg CO₂e

Bus stations and stops in Brno and Prague

Stops in Brno

A
Brno Bus Station
Brno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia
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B
Hotelu Grand
Benešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic
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C
Hlavní nádraží
Nádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia
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D
ÚAN Zvonařka
Zvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic
Visit page
E
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia
F
Ústřední hřbitov
Vídeňská 306/94, Štýřice, 639 00 Brno-Brno-střed, Czechia

Stops in Prague

A
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
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B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
C
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
D
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare companies

FlixBus

3.5/513,104 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

RegioJet

4.1/51,083 reviews

Staff4.5

Timeliness4.0

Cleanliness4.4

Wifi3.8

Slovak Lines

4.5/5168 reviews

Staff4.8

Timeliness4.8

Cleanliness5.0

Wifi4.2

A-Express

IC Bus

4.5/520 reviews

Staff5.0

Timeliness5.0

Cleanliness5.0

Gepard Express

Monobus

1.5/52 reviews

Staff5.0

Timeliness2.5

Cleanliness0.0

Wifi0.0

CZ bus companies:FlixBus, BlaBlaCar Bus, Sindbad, Ecolines, KLR Bus, RegioJet, Agat

Frequently asked questions about traveling from Brno to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Brno to Prague?
The cheapest bus tickets from Brno to Prague start from HK$81. The average price for this route is around HK$119. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brno to Prague?
The average bus trip duration from Brno to Prague is 2h 35m, covering a distance of 117 miles (188 km). The quickest bus can get you there in 2h 20m and is operated by FlixBus.
Which bus companies service the Brno to Prague route?
Several major bus companies operate on this route with 65 buses available per day, including services from FlixBus, RegioJet, Slovak Lines, A-Express, IC Bus, Gepard Express, Monobus.
What is the earliest and latest departure time for the bus from Brno to Prague?
The earliest bus departs from Brno to Prague at 1:30am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Brno to Prague?
A bus trip from Brno to Prague generates an estimated 4.688375 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brno to Prague?
According to Busbud customers, the highest-rated bus company on this route is Slovak Lines, with an average rating of 4.5 out of 5 stars based on 168 reviews.
Which bus company has the best Wi-Fi from Brno to Prague?
Based on reviews on Busbud, the bus company Slovak Lines has the best Wi-Fi rating with a score of 4.2.
Which bus company has the most timely service from Brno to Prague?
According to Busbud traveler reviews, the most timely bus company on this route is IC Bus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Brno to Prague?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is IC Bus, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07/28

HK$79

07/29

HK$79

Today

HK$80

07/31

HK$80

08/01

HK$85

08/02

HK$85

08/03

HK$79

08/04

HK$80

The cheapest trip from Brno to Prague was searched and found on Jul 28, 2026 with a price of HK$79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brno to Prague, as early as possible.

You can expect to pay from HK$79 to HK$283 for a bus ticket from Brno to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at HK$79 which is on 2026-08-03.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.